There are many websites that specialize in this, but I usually just do this:

Enter your route into Yahoo Maps Driving directions (the new beta):

Your route on Yahoo Maps

On the map you will see a little check box "Live Traffic".

That should give you up to date information (usually its more recent then most government websites).

For your trip I see two fires affecting you:

You get these little pop up bubbles when you hover with your mouse over any of the markers.

The map also shows accidents and traffic jams. I find it a very good resource for last minute information. I sometimes even use it if I need to go somewhere during the day, to decide on the best route (avoiding slow moving traffic).

Let me know you have trouble with Yahoo Maps (you need to use the new version, not the old).

Wow  I never knew that they had something like this. I would have never thought to look up roads that might be blocked because of the wildfires. I will have to pass this one on to my parents. They are leaving for Colorado next weekend.

Yahoo has a lot of good stuff. Unfortunately their site is so large, that its sometimes hard to find exactly what you are looking for. I even find myself using them for searching more often now.

I just realized that there was another thread about Florida Highway Closings due to fires.

We are having issues up here in South Carolina due to  heavy smoke conditions as well.  Amazingly, the smoke is coming all the way from Florida.  It was burning my eyes yesterday and it was tough to breathe.

I would suggest to most people to stay away from this area altogether right now. 

Florida needs a certain amount of fire every year to keep the pine forests healthy.  The pine cones don't open enough to actually seed unless they reach the really high temperatures that come from fire.  If there are no fires, the forests get old, and even drier.  There are campaigns now to get private owners to clear their land of underbrush, the way the Indians used to, to cut the fire and actually make the forest more 'natural', i.e. the way they were when the colonists arrived.

 But this much we can do without.

And that Yahoo! stuff is really cool.

We just came back from this area a day ago. The smell of the fires from Atlanta to around Cordelle is pretty smokey but the roads were clear. The Bugaboo fire is 90% contained which is the area of the Ga/Florida border. No road closings as of the other day. There is construction though that can bog things down. But it was good for us.

Georgia's fires is most likely what you are smelling. Georiga might go on total restrictions with water, meaning no lawn watering at all. That's how bad it is. I have a vacation home in Dahlonega (northeast Ga) and although our forrest is fine, there is a drought there too. Typically that has been more moist. Florida's fires is not as bad as Ga. (so far)